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Trend Report

Flow chemistry for sustainable pharmaceutical manufacturing

 

Trend report

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Sustainable Manufacturing

As one of the more prominent industries producing greenhouse gas emissions, the pharmaceutical industry has had to reckon with the impact of their operations across all sectors, including active pharmaceutical ingredient (API) manufacturing. While the API manufacturing sector is already seeing innovation in more sustainable ways of working, there is still room for improvement.


Continuous flow chemistry is one such transformational technology that has caught the attention of pharmaceutical manufacturers. As a technology already in use in laboratories and larger-scale manufacturing in certain chemical industries, flow chemistry has the potential to enhance API manufacturing operations while bringing many Green Chemistry principles to pharmaceuticals.


Though the technology has yet to prove its viability in commercial-level production plants, especially given the stringent manufacturing regulations demanded of pharma, experts across the pharmaceutical value chain are confident in the innovative and sustainable future provided by flow chemistry technologies.


In partnership with Asymchem, and with expert insight from those at Amgen, the University of Liverpool, CONTINUUS Pharmaceuticals, and Fraunhofer IMM, this Trend Report takes a deeper look into the sustainable transformations offered by continuous flow chemistry technology, and the power it boasts when optimised for the specific manufacturing need.

Contributors including

With thanks to our contributors for their time and expertise

Jon Brice

Senior Vice President of Business Development

Asymchem Group

Mingshu Li

Senior Director of Business Development

Asymchem Group

Gabriele Menges-Flanagan

Senior Scientist

Fraunhofer IMM

Stephen Born

Senior Director, Head of Scientific Affairs

CONTINUUS Pharmaceuticals

Dr Firdaus Parveen

Liverpool Digital Flow Centre Manager and Research Coordinator –

University of Liverpool

Anirudh Nambiar

Senior Engineer, Process Development

Amgen

The Trend Report covers

  • Sustainable manufacturing in pharma: current practices and challenges
  • Green Chemistry and the pharmaceutical industry
  • Flow chemistry technologies for pharma
  • API manufacturing for a sustainable future
  • The future of sustainable API manufacturing